I had the same problem with multiple vendors. Installing the latest update for my MacOS 12 along with a Safari update did not resolve the problem. I eventually determined the source of the problem and only a partial solution. (This was my experience. Your mileage may vary.) I went into Safari -> Preferences... -> Extensions -> Disabled 'Rakuten Cash Back' -> Closed the Preferences window. Next, I went back into preferences and re-enabled the Rakuten extension and closed the preferences window. (It didn't work to simply disable & re-enable the Rakuten extension without closing the Preferences window after disabling.) That allowed me to check out with PayPal. One caveat... If I choose the Rakuten discount, the problem comes back. I have not tested other options like installing and testing Rakuten on a different browser such as Chrome, Firefox or Brave. I have not tried using 'Honey' instead of 'Rakuten'. I disabled Honey a while back because it was revving up the CPUs too much resulting in system slowdowns. That was a long while back and may have been resolved since then.
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